No association between germline allele-specific expression of TGFBR1 and colorectal cancer risk in Caucasian and Ashkenazi populations.

Tipo de Publicación:

Journal Article

Autores:

Seguí, N; Stevens, KN; Guinó, E; Rozek, LS; Moreno, VR; Capellá, G; Gruber, SB; Valle, L

Origen:

British journal of cancer, Volumen 104, Ejemplar 4, p.735-40 (2011)

URL:

http://dx.doi.org/10.1038/sj.bjc.6606079

Resumen:

Germline allele-specific expression (ASE) of the TGFBR1 gene has been reported as a strong risk factor for colorectal cancer (CRC) with an odds ratio close to 9. Considering the potential implications of the finding, we undertook the task of validating the initial results in this study.

Pubmed ID: 21224855